Mastering Cannabis Delivery Methods and Dosing

How Our Bodies Metabolize Cannabis 

The type of cannabis and the method of which its consumed directly affects how it works as medicine in our bodies. Unique chemistries of different types of cannabis are metabolized by our bodies differently. The media is great at portraying cannabis use which encourages users to develop a distorted sense of frequency and size of appropriate cannabis dosing (such as movies and television shows).  The delivery method determines the speed and efficiency with which cannabis works and how long the effects will last. So, mastering cannabis delivery methods and dosing is very important.

Cannabis Shelf Life & Contaminants 

cannabis, being a natural product has a shelf life of course. Knowing how to properly store cannabis will help extend its shelf life (learn how to properly store you cannabis by reading our article-”Cannabis Storage Methods”. On occasion, there is more than just the cannabis itself that should rightfully be there. So, it’s very important to learn how to spot different contaminants and knowing which contaminants require laboratory testing to detect them. 

Cannabis Delivery Methods and Dosing 

In order to treat your specific medical condition with cannabis, the most important thing of all is learning cannabis delivery methods and dosing

Cannabinoids and Solubility 

One of the biggest issues when using cannabis is its cannabinoids. The issue with cannabinoids is that they hate water and absolutely LOVE fat. Let’s get technical for just a minute. So, cannabinoids are hydrophobic and lipophilic. In general, for the most part-medicine is taken orally and this insolubility in water poses some big issues. cannabinoids are not absorbed very well when taken orally. Due to this deviation, cannabinoid medicines were not favorable during the 1940’s, but that can be expected when knowledge is minimal. Fast forward to the last 20 years however, and researchers known much more about how cannabinoids and cannabis can be absorbed more effectively, not only from sublingual deliver, but vaporization methods as well.  

The main point of these delivery methods is intended to avoid the gut and to deliver cannabis to the bloodstream in the quickest way possible. 

Cannabis Dosing 

The most realistic approach to dosing cannabis is by starting with the smallest effective dose which will deliver the desired symptomatic relief possible. This approach emphasizes a small, controlled, and measured dosage to cannabis.  

Cannabis Overmedicating and Tolerance 

Tools such as bongs (water pipes) and vaporizers don’t have detailed instructions included telling the user how to control their dosage of cannabis. Take a “joint” for instance. A joint cannot provide dose guidance. Typically, a joint can contain anywhere from 0.25g to 1g of cannabis.

So, many times-new user’s to cannabis will overmedicate. Consistently overmedicating with cannabis becomes a problem because it can lead to tolerance of the medicinal effects of cannabis. cannabis tolerance results in increasing the dosage in order to properly relieve symptoms that would have been relieved originally by smaller doses

Marinol Dose Guidance and THC-Dominant Cannabis 

dose guidance becomes even more useful when using THC-dominant cannabis due to their highly psychoactive effects. But how is a dose determined? Marinol, which is a prescription synthetic form of THC is currently the best studied cannabis. The reason for this is that Marinol has clear dosage guidelines, are well understood, and can provide a starting point for creating dosage guidelines for cannabis

Marinol, which is a prescription synthetic form of THC is currently the best studied cannabis. The reason for this is that Marinol has clear dosage guidelines, are well understood, and can provide a starting point for creating dosage guidelines for cannabis

For appetite stimulation, Marinol starts at 2.5-milligrams of THC. Depending on a patient’s height and weight- a dose of Marinol can exceed 15-milligrams. 

Psychoactivity 

cannabis users can typically notice psychoactivity at a dose of 5-milligrams of THC, so it’s no surprise that a 15-milligram dose of THC can produce high levels of psychoactivity which may very well be unpleasant. However, recent studies have shown that cannabis doses delivering between 2.5 and 10 milligrams of THC can help a wide range of symptoms, resulting with tolerable levels of psychoactivity. In addition, increased evidence that the other primary cannabinoid, CBD (which is found in some varieties of cannabis), can in fact minimize THC’s psychoactivity levels. When cannabis is dosed correctly, it can also be very effective both sublingually and orally.  

The Downside to Oral Cannabis 

The only minor downside to this is that it can take 45 to 180 minutes for oral cannabis to take effect. On the other hand, delta-9-THC when taken sublingually, the effects can be achieved within five minutes because it is absorbed directly into the bloodstream. 

The Upside to Oral Cannabis 

The upside to oral cannabis is that it is effective two to three times longer than vaporized or smoked cannabis, which therefore reduces the need for repeated use. 

However, recent studies have shown that cannabis doses delivering between 2.5 and 10 milligrams of THC can help a wide range of symptoms, resulting with tolerable levels of psychoactivity. In addition, increased evidence that the other primary cannabinoid, CBD (which is found in some varieties of cannabis), can in fact minimize THC’s psychoactivity levels. 

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