Crohn’s Disease | Cannabis Wiki

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Crohn’s Disease

Crohn’s disease is a condition affecting the gastrointestinal tract which results in inflammation and scarring of the intestinal wall. It is a persistent condition characterized by periods of active disease and remission.

Crohn’s disease is one of the family of diseases termed inflammatory bowel disease, although the condition can affect any part of the tract from the mouth to the anus. The small bowel is the major site of involvement (about 801 percent of cases), and there is a large bowel (colonic) disease in 50 percent of cases.

Symptoms of Crohn’s Disease

Symptom’s of Crohn’s disease are often similar to those of ulcerative colitis, the other major inflammatory bowel disease. Symptoms vary according to site, severity and extent of the disease. The small bowel is the main site for the absorption of digested food, nutrients, and disease in this area may result in malabsorption. Disease affecting the colon may lead to the passage of blood in feces, and incontinence may occur in rectal disease. Oral Crohn’s disease often causes persistent mouth ulcers.

The following general symptoms are typical when the disease is active:

  • Pain
  • Urgent diarrhea
  • Weight loss
  • Mild fever

Causes of Crohn’s Disease

No single cause of Crohn’s disease has yet been identified. It is probable that genetic factors place a predisposed individual at greater risk of developing the disease when exposed to ‘trigger’ environmental factors.

Genetic Factors

There is an increased incidence of the disease in relatives of patient’s with Crohn’s disease.

Environmental Factors

Several infectious agents, including the measles virus and an organism called Mycobacterium tuberculosis have been implicated as possible causing agents for Crohn’s disease, but studies have failed to prove a definite link between the two.

Diet

High intake of refined sugars and low intake of fiber have been suggested as possible causes, but evidence is weak.

Smoking

This is more common in Crohn’s sufferers disease than in unaffected people, and is associated with more frequent relapse of the disease.

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